Certain gram negative bacteria possess a complex protein secretion apparatus known as the type three secretion system (TTSS) which delivers effector protein into the cytoplasm of eukaryotic cells in order to modulate host cellular functions.

Key Benefits

Traditional methods of vaccine development necessitate the production of large quantities of antigens, can be expensive and require the use of adjuvants which can increase levels of immunogenicity.

A highly simple production process combined with the fact that adjuvants are not needed ensures that Screenvac can radically increase the speed at which antigens can be discovered.

Potential applications

The inventors intend to use their technology to develop a service platform for in vivo antigen screening. The technology is of specific interest to healthcare professionals working in the following fields

• Vaccines
• Antigen screening and optimization
• Cancer and other infectious diseases
• Human and animal healthcare

IP Status

Protected by Patent n°W02005049644

Polack B., Toussaint B., Quénée L. (2005) Tool for the transfer and production of proteins using Pseudomonas type III se-cretion system.

Contact
Pascale Grenard-Ecuyer
Technology Transfer Manager
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Tel. +33 (0)4 76 00 78 34