In Ovo Screening : assessment of electromagnetic radiation PDF Print E-mail

An Innovative technology that enables the fast and efficient evaluation of the impact of electromagnetic waves on embryonic development

Introduction

The ability to quickly and efficiently evaluate the effect of intense, long-term electromagnetic exposure on humans and on embryonic development is a key requirement in public healthcare.

In ovo screening is an innovative technology that provides a solution to this problem: via an analytical model that works on both macroscopic and molecular levels.

The in ovo model enables a clear understanding of the possible effects of electromagnetic exposure on humans as well as reducing the need to carry out scientific experiments on animals.

oeufs.jpgFrequency / Exposure times

The model enables the evaluation of electromagnetic exposure on embryos and organs during development by first carrying out tests in-ovo (eggs can be exposed for up to 20 consecutive days and frequency/exposure times can be modified according to experimental demands).

Services Available

  • Analysis of embryonic development at different stages of development (daily observation increases the accuracy of the final analysis)
  • Macroscopic analyses for the detection of potential malformations or mortality induced by treatment
  • Histological and molecular analyses (in situ hybridization, immuno-histochemistry, cell cultures, biomarkers, genotoxicity...)
  • Comparative analyses, correlation between phenotypic results and molecular pathway networks, databank analyses

The benefits of in ovo testing

The model allows results to be obtained after embryos have been subjected to constant electromagnetic exposure (equivalent tests on animals prove less effective as they are prone to movement, thereby reducing levels of electromagnetic exposure).

  • Strong similarities with human embryonic development enables cross-tabulation with human based studies including all of the following
    - embryonic development
    - cellular differentiation
    - molecular pathways and organogenesismachine.jpg
  • Very strong/total similarity with mammals for
    -  physiology
    -  metabolism
    -  molecular pathways
  • Possible to test on a very large number of samples at the same time
  • Confirmation of results obtained from cells
  • Optimization of R&D programs focusing on electromagnetic exposure
  • Reduction of risk in R&D  programs through a cost-effective methodology

Potential Applications

►Telephony: risk assessment

►High voltage networks: risk assessment

►Electric devices etc.

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Commercial opportunities

Floralis is currently looking for industrial partners who may benefit from this technology as part of their R&D programs.

Florence Alesandrini
Technology Transfer
Tél. +33 (0)4 76 00 78 35
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