Improved outcome of artificial insemination and in vitro fertilization by increasing male fertility

Introduction

About 15% of couples have infertility problems, half of which is due to deficiencies of man. Despite undeniable progress, many infertile couples fail to conceive. Moreover, the risk of giving birth to a child with a rare genetic disease, although very low, is significantly higher in children born using ART. Several reasons were cited including a higher risk of defective sperm selection in ART compared to processes of natural selection. In this context, the quality of gametes is of particular importance. The discovery described below, if transposed to humans, would enable to select the best sperm quality for ART. If transposed to other animals, this technology would improve the yield of artificial insemination techniques.