Epstein Barr Virus R Transactivator (RTA) Technology PDF Print E-mail

A novel antibody enabling the detection and qualification of the RTA protein, a key factor in the detection of early Epstein Barr Virus.

Introduction

The R Transactivator (RTA) is one of the two main transactivators originating from the Epstein Barr Virus (EBV). It acts in synergy with the Zebra protein in the switch-latency productive cycle.  The transactivator demonstrates significant potential as a marker for the early detection of EBV infection. This technology is available to license to organisations working in the field of monoclonal antibody distribution.

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Features/Benefits

  • Monoclonal Antibody
    • Highly targeted
  • Validated for use in immunofluorescence/western blotting/Flow cytometry
    • Facilitates use in a research environment
  • UVHCI (Unit of Virus Host Cell Interactions), laboratory renowned at a European level
    • Specialists in the understanding of EBV biology

Applications

  • Detection of early Epstein Barr Virus infection
  • The technology has significant potential within a research environment

Scientific data

Name Anti EBV R transactivator (Rta)
Clone 5A9 (IgG) // 8c12 (IgG) //4C1 (IgG)
Host species :
Mouse
Ig subclass :
Mouse monoclonal IgG
Culture medium RPMI 1640 with FCS GIBCO (Invitrogene) 10%

 

 

 

 

 

References :

Imbert-Marcille et al. Clin. Diagn. Lab Immunol. 7 : 206-211.2000
Feederle R. et al. EMBO J. 19 : 3080-3089.2000

Commercial Opportunities

This technology is available to license to organisations working in the field of monoclonal antibody distribution.

Contact
Technology Transfer Manager
Pascale Grenard-Ecuyer
+33 476 00 78 34
This e-mail address is being protected from spambots. You need JavaScript enabled to view it

 

 

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